A farmer unearths an old top hat on his property and with it an ancient Indian curse that lays waste to all the farmers crops. All of the adults of the farming community are afflicted by a strange sickness that slowly dries them up until they are dust. It is only when the farmer communes with the hat does he find what it is that will save them all.

A psychotic college professor uses unwitting students as laboratory rats, injecting them with a drug that mutates them into gory killers.